1D system simulation is now well deployed over the engine development cycle, especially for engine and component design. 1D codes have been used for years in two very distinct areas: for the simulation of the gas dynamics in the air path in order to evaluate engine performance, and as a support for the design of the actuators allowing the connection of hydraulic and pneumatic, mechanical and electrical components. During the engine integration stage, the set-up of the actuator on the engine and the calibration of the associated control strategies are generally achieved on the test bench which leads to a time and cost consuming process. The use of a dedicated model for the analysis and optimization of the integration of the engine actuation system represents a real added value. Being able to assess the first steps of the calibration of the control strategies in a virtual environment enables to significantly reduce the time and cost when compared to conventional testing approaches. This paper aims at illustrating the capabilities offered by 1D system simulation to cover a broader range of the engine development cycle, from engine detailed design to actuator and control integration. A proof-of-concept completes the theoretical methodology, detailing a practical application of variable valve actuation system. The model developed includes the intake and exhaust systems, the VVT actuator, the combustion chamber and a first level of control strategy. The aim is to simulate the impact of the valvetrain control strategies on the combustion process.